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David Hesk Selected Research

SCH 900567

9/2014Synthesis of [(3) H], [(13) C3 , (15) N], and [(14) C]SCH 900567: an inhibitor of TNF-α (tumor necrosis factor alpha) converting enzyme (TACE).

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David Hesk Research Topics

Disease

3Alzheimer Disease (Alzheimer's Disease)
12/2022 - 01/2016
2Neurodegenerative Diseases (Neurodegenerative Disease)
10/2016 - 01/2016
1Schizophrenia (Dementia Praecox)
01/2022
1Substance-Related Disorders (Drug Abuse)
01/2022
1Parkinson Disease (Parkinson's Disease)
01/2022
1Neoplasms (Cancer)
07/2018
1Dehydration (Water Stress)
01/2016
1Peripheral Arterial Disease
09/2015
1Myocardial Infarction
09/2015
1Rheumatoid Arthritis
09/2014

Drug/Important Bio-Agent (IBA)

1Muscarinic M4 ReceptorIBA
12/2022
1Trace Amine-Associated ReceptorsIBA
01/2022
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2022
1MK-8353IBA
07/2018
13(S)-thiomethyl pyrrolidineIBA
07/2018
1tau Proteins (tau Protein)IBA
01/2016
1pyrazoleIBA
01/2016
1vorapaxarIBA
09/2015
1Peptide Hydrolases (Proteases)FDA Link
09/2015
1ADAM17 ProteinIBA
09/2014
1SCH 900567IBA
09/2014

Therapy/Procedure

2Therapeutics
07/2018 - 10/2016